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Phox2btm1.1(cre)Tvrd
Targeted Allele Detail
Summary
Symbol: Phox2btm1.1(cre)Tvrd
Name: paired-like homeobox 2b; targeted mutation 1.1, Petr Tvrdik
MGI ID: MGI:8224279
Synonyms: Phox2b-IRES-Cre
Gene: Phox2b  Location: Chr5:67251751-67256399 bp, - strand  Genetic Position: Chr5, 35.95 cM
Alliance: Phox2btm1.1(cre)Tvrd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:353275
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Phox2btm1.1(cre)Tvrd expression driven by 1 gene
 
Mutation details: An IRES-Cre-FRT-neo-FRT cassette was inserted in the 3' untranslated region of the endogenous Phox2b gene. FLP-mediated recombination removed an frt-flanked selection cassette. (J:353275)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Phox2b (mouse)
Summary of all recombinase alleles driven by Phox2b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Phox2b Mutation:  22 strains or lines available
References
Original:  J:353275 Watson C, et al., Spinal Accessory Motor Neurons in the Mouse: A Special Type of Branchial Motor Neuron?. Anat Rec (Hoboken). 2019 Mar;302(3):505-511
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory