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Tg(Trp53-Cre/ERT2)1Zzy
Transgene Detail
Summary
Symbol: Tg(Trp53-Cre/ERT2)1Zzy
Name: transgene insertion 1, Zhongzhou Yang
MGI ID: MGI:8224274
Synonyms: p53-Mer-Cre-Mer BAC
Transgene: Tg(Trp53-Cre/ERT2)1Zzy  Location: unknown  
Alliance: Tg(Trp53-Cre/ERT2)1Zzy page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Mutation:    Insertion
 
Tg(Trp53-Cre/ERT2)1Zzy expression driven by 1 gene
 
Mutation details: An ERT2CreERT2-IRES-EGFP cassette followed by p53 3UTR-SV40 poly A cassette was inserted into p53 BAC (No.bMQ-441J16) at the ATG codon in the second exon of p53 gene via recombination. The BAC was used to generate transgenic mice. (J:354930)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Trp53 (mouse)
Summary of all recombinase alleles driven by Trp53.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:354930 Xiao Q, et al., A p53-based genetic tracing system to follow postnatal cardiomyocyte expansion in heart regeneration. Development. 2017 Feb 15;144(4):580-589
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
08/05/2025
MGI 6.24 		The Jackson Laboratory