C3tm1Lgmo
Targeted Allele Detail
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| Symbol: |
C3tm1Lgmo |
| Name: |
complement component 3; targeted mutation 1, Lori G Morton |
| MGI ID: |
MGI:8224026 |
| Gene: |
C3 Location: Chr17:57510970-57535136 bp, - strand Genetic Position: Chr17, 29.72 cM, cytoband E1-E3
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| Alliance: |
C3tm1Lgmo page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:369997
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129 x C57BL/6
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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| |
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Mutation details: The gene, including the 5' regulatory elements and all of the coding exons 1 through 41, were replaced with a lacZ-loxP-neo-loxP cassette.
(J:369997)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any C3 Mutation: |
100 strains or lines available
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|
| Original: |
J:369997 Devalaraja-Narashimha K, et al., Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy. J Am Soc Nephrol. 2021 Jan;32(1):99-114 |
| All: |
1 reference(s) |
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Analysis Tools
