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Serinc2em1(icre)Cln
Endonuclease-mediated Allele Detail
Summary
Symbol: Serinc2em1(icre)Cln
Name: serine incorporator 2; endonuclease-mediated mutation 1, Marco Colonna
MGI ID: MGI:8223570
Synonyms: Serinc2iCre
Gene: Serinc2  Location: Chr4:130147289-130172993 bp, - strand  Genetic Position: Chr4, 63.43 cM
Alliance: Serinc2em1(icre)Cln page
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Serinc2em1(icre)Cln expression driven by 1 gene
 
Mutation details: IRES sequence and sequence coding for codon improved Cre recombinase were inserted downstream of the endogenous stop codon. (J:369928)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Serinc2 (mouse)
Summary of all recombinase alleles driven by Serinc2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serinc2 Mutation:  24 strains or lines available
References
Original:  J:369928 Rodrigues PF, et al., Rorgammat-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens. Cell. 2025 May 15;188(10):2720-2737.e22
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory