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Tg(Defa24-icre)1Clib
Transgene Detail
Summary
Symbol: Tg(Defa24-icre)1Clib
Name: transgene insertion 1, Claude Libert
MGI ID: MGI:8204665
Transgene: Tg(Defa24-icre)1Clib  Location: unknown  
Alliance: Tg(Defa24-icre)1Clib page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Defa24-icre)1Clib expression driven by 1 gene
 
Mutation details: The mouse gene drives expression of the improved cre recombinase gene. Four transgenic lines were established, but only one with expression selectively in Paneth cells was chosen for further analysis. (J:367495, J:370139)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Defa24 (mouse)
Summary of all recombinase alleles driven by Defa24.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:370139 Garcia-Gonzalez N, et al., Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line. Front Immunol. 2025;16:1576995
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory