About   Help   FAQ
Mki67em1(dre/ERT2)Ben
Endonuclease-mediated Allele Detail
Summary
Symbol: Mki67em1(dre/ERT2)Ben
Name: antigen identified by monoclonal antibody Ki 67; endonuclease-mediated mutation 1, Rui Benedito
MGI ID: MGI:8192605
Synonyms: MKi67-2A-DreERT2
Gene: Mki67  Location: Chr7:135291513-135318090 bp, - strand  Genetic Position: Chr7, 81.32 cM, cytoband F3-F5
Alliance: Mki67em1(dre/ERT2)Ben page
Mutation
origin
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mki67em1(dre/ERT2)Ben expression driven by 1 gene
 
Mutation details: CRISPR-targeting introduced in frame the viral 2A peptide followed by the inducible dre recombinase fusion gene (2A-dre/ERT2) before the Mki67 gene stop codon. (J:366224)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mki67 (mouse)
Summary of all recombinase alleles driven by Mki67.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mki67 Mutation:  142 strains or lines available
References
Original:  J:366224 Garcia-Gonzalez I, et al., iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cells. Nat Methods. 2025 Feb;22(2):323-334
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory