Tg(CAG-dre/ERT2)1Ben Transgene Detail MGI Mouse (MGI:8192603)

Tg(CAG-dre/ERT2)1Ben
Transgene Detail

Summary

Symbol:	Tg(CAG-dre/ERT2)1Ben
Name:	transgene insertion 1, Rui Benedito
MGI ID:	MGI:8192603
Synonyms:	Tg(INS-CAG-DreERT2)
Transgene:	Tg(CAG-dre/ERT2)1Ben Location: unknown
Alliance:	Tg(CAG-dre/ERT2)1Ben page

Mutation
origin

Strain of Origin:

(129S6/SvEvTac x C57BL/6NCrl)F1

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Mutation:

Insertion

Tg(CAG-dre/ERT2)1Ben expression driven by 1 gene

Mutation details: CRISPR-targeting of Tg(CAG-flpo/ERT2)2Ben replaced the flpo recombinase with the dre recombinase. The transgene remains flanked by insulator sequences. (J:366224)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:366224 Garcia-Gonzalez I, et al., iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cells. Nat Methods. 2025 Feb;22(2):323-334
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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