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Tg(CAG-CD2,-flpo,-dre/ERT2)PBen
Transgene Detail
Summary
Symbol: Tg(CAG-CD2,-flpo,-dre/ERT2)PBen
Name: transgene insertion P, Rui Benedito
MGI ID: MGI:8192478
Synonyms: Tg-iDre/FlpProgenitor
Transgene: Tg(CAG-CD2,-flpo,-dre/ERT2)PBen  Location: unknown  
Alliance: Tg(CAG-CD2,-flpo,-dre/ERT2)PBen page
Transgene
origin
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Transgene
description
Transgene Type:    Transgenic (Epitope tag, Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(CAG-CD2,-flpo,-dre/ERT2)PBen expression driven by 1 gene
 
Mutation detailsThe transgene contains the CAG, Rox site, FRT545 site, transcription stop cassette, FRT545 site, Rox site, histone 2B chromatin/nucleus tag and KOZAK sequence plus C-terminal paramyxovirus V5 tag sequence, 2A sequences, human CD2 reporter gene, 2A sequence, flpo recombinase gene, 2A sequence, and inducible dre recombinase fusion gene (dre/ERT2), WPRE sequence, and polyadenylation sequence. (J:366224)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:366224 Garcia-Gonzalez I, et al., iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cells. Nat Methods. 2025 Feb;22(2):323-334
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory