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Krt14em1(cre/ERT2)Bcgen
Endonuclease-mediated Allele Detail
Summary
Symbol: Krt14em1(cre/ERT2)Bcgen
Name: keratin 14; endonuclease-mediated mutation 1, Biocytogen LLC
MGI ID: MGI:8163440
Gene: Krt14  Location: Chr11:100093988-100098336 bp, - strand  Genetic Position: Chr11, 63.43 cM, cytoband D
Alliance: Krt14em1(cre/ERT2)Bcgen page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Krt14em1(cre/ERT2)Bcgen expression driven by 1 gene
    The CreERT2 cassette is under the control of the Krt4 promoter. (J:322611)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt14 (mouse)
Summary of all recombinase alleles driven by Krt14.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt14 Mutation:  34 strains or lines available
References
Original:  J:322611 Han H, et al., N(7)-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis. Nat Commun. 2022 Mar 18;13(1):1478
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory