Gt(ROSA)26Sortm11(CAG-cre/ERT2,-flpo,-tdTomato*)Ben
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm11(CAG-cre/ERT2,-flpo,-tdTomato*)Ben |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 11, Rui Benedito |
| MGI ID: |
MGI:8161960 |
| Synonyms: |
iSuRe-HadCre |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm11(CAG-cre/ERT2,-flpo,-tdTomato*)Ben page
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| Allele Type: |
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Targeted (Inducible, Recombinase, Reporter) |
| Mutation: |
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Insertion
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Gt(ROSA)26Sortm11(CAG-cre/ERT2,-flpo,-tdTomato*)Ben expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: The targeting construct inserted into the locus a CAG promoter, FRT site, loxP site, triple stop codons, loxP site, cre recombinase gene,loxN site, modified estrogen receptor (ERT2), loxN site, in-frame Thosea asigna virus 2A cleavage site (T2A; mediates ribosomal skipping), flpo recombinase gene, FRT site, and the Mb-Tomato gene (non-oligomerizing tandem-dimer DsRed fluorescent protein variant tdTomato with N-terminal 41 amino acid membrane-targeting tag sequence).
(J:352091)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
1093 strains or lines available
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| Original: |
J:352091 Garcia-Gonzalez I, et al., iSuRe-HadCre is an essential tool for effective conditional genetics. Nucleic Acids Res. 2024 Jul 22;52(13):e56 |
| All: |
2 reference(s) |
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Analysis Tools
