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Tg(Pyy-cre)1Able
Transgene Detail
Summary
Symbol: Tg(Pyy-cre)1Able
Name: transgene insertion 1, Andrew B Leiter
MGI ID: MGI:8161172
Synonyms: Pyy-Cre
Transgene: Tg(Pyy-cre)1Able  Location: unknown  
Alliance: Tg(Pyy-cre)1Able page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pyy-cre)1Able expression driven by 1 gene
 
Mutation detailsA bacterial artificial chromosome, BAC, (Incyte Genomics168M3) containing the mouse peptide YY (Pyy) gene was modified so that the Pyy promoter drives expression of a constitutively active cre recombinase (cre) gene. The BAC contains 117 kb of genomic DNA upstream of the Pyy locus and 130 kb downstream. The transgene also contains an FRT site leftover from the removal of an FRT-flanked kanamycin resistance cassette. (J:98886, J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pyy (mouse)
Summary of all recombinase alleles driven by Pyy.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:98886 Schonhoff S, et al., Energy homeostasis and gastrointestinal endocrine differentiation do not require the anorectic hormone peptide YY. Mol Cell Biol. 2005 May;25(10):4189-99
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory