P2rx7tm1(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
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| Symbol: |
P2rx7tm1(EGFP/cre/ERT2)Wtsi |
| Name: |
purinergic receptor P2X, ligand-gated ion channel, 7; targeted mutation 1, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:7867275 |
| Gene: |
P2rx7 Location: Chr5:122781974-122829495 bp, + strand Genetic Position: Chr5, 62.5 cM, cytoband F
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| Alliance: |
P2rx7tm1(EGFP/cre/ERT2)Wtsi page
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| Mutant Cell Line: |
CEPD0050_3_A08 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:82809
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| Parent Cell Line: |
JM8.N4 (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Allele Type: |
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Targeted (Conditional ready, Inducible, Null/knockout, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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P2rx7tm1(EGFP/cre/ERT2)Wtsi expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The following elements were inserted into intron 1: FRT site, En2 splice acceptor sequence, sequence coding for F2A self-cleaving peptide, EGFP reporter gene, sequence coding for T2A self-cleaving peptide, cre/ERT2 inducible recombinase gene, SV40 poly(A) signal sequence, Rox site flanked puromycin resistance gene cassette, and a loxP site. A second loxP site was inserted into intron 2. This creates a reporter-recombinase knockout allele with a floxed exon 2.
(J:82809)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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P2rx7
(mouse)
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| Original: |
J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013; |
| All: |
1 reference(s) |
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Analysis Tools
