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Gene Expression Data
Assay Details
Assay
Reference: J:359864 Chen Y, et al., The Ednrb-Aim2-AKT axis regulates neural crest-derived melanoblast proliferation during early development. Development. 2024 Nov 15;151(22):dev202444
Assay type: RNA in situ
MGI Accession ID: MGI:7861720
Gene symbol: Mitf
Gene name: melanogenesis associated transcription factor
Probe: Mitf cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A WT Mitf: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: migrating neural crest melanoblast Present Widespread 1A WT Mitf , 1A WT Mitf inset Expression in migratory melanoblasts throughout cranial, trunk and sacral regions.
Specimen 1A Ednrb-/- Mitf: embryonic day 11.5; Ednrbtm1Myks/Ednrbtm1Myks (more )
Structure Cell Type Level Pattern Image Note
TS19: migrating neural crest melanoblast Weak Regionally restricted 1A Ednrb-/- Mitf inset , 1A Ednrb-/- Mitf Expression reduced compared to wild type, limited to sacral and caudal areas.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory