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Gene Expression Data
Assay Details
Assay
Reference: J:160115 Parent AE, et al., Slug (Snai2) expression during skin and hair follicle development. J Invest Dermatol. 2010 Jun;130(6):1737-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7861272
Gene symbol: Snai2
Gene name: snail family zinc finger 2
Antibody: Anti-Slug (C19G7) #9585
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1a E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: surface ectoderm Present Single cells 1a E11 Slug Expression is in scattered cells of the single-layered epidermis.
TS18: embryo mesenchyme Present Regionally restricted 1a E11 Slug Expression is in most of the primitive mesenchyme underlying the single-layered epidermis.
Specimen 1a E14: embryonic day 14.0 (more )
Structure Cell Type Level Pattern Image Note
TS22: epidermis basal layer keratinocyte Present 1a E14 Slug Expression is in basal keratinocytes.
Specimen 1a E17: embryonic day 17.0 (more )
Structure Cell Type Level Pattern Image Note
TS25: epidermis basal layer keratinocyte Present 1a E17 Slug Expression is in basal keratinocytes.
Specimen 1b: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: hair epidermal placode Present 1b Slug
TS22: hair follicle dermal papilla Absent 1b Slug
Specimen not shown E10: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: surface ectoderm Present Single cells Expression is in scattered cells of the single-layered epidermis.
TS16: embryo mesenchyme Present Regionally restricted Expression is in most of the primitive mesenchyme underlying the single-layered epidermis.
Specimen not shown E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: dermis Present
TS20: epidermis Present
Specimen 2b Day 1: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: hair outer root sheath Present 2b Day 1
TS27: hair root sheath matrix Present 2b Day 1
TS27: epidermis basal layer keratinocyte Present Regionally restricted 2b Day 1 Expression is in many, but not all, basal keratinocytes and are clustered around hair follicles.
TS27: hair follicle dermal papilla Present Regionally restricted 2b Day 1 Expression is in some mesenchymal cells.
TS27: interfollicular epidermis Present Regionally restricted Expression is in the basal layer of the interfollicular epithelium.
Specimen 2b Day 5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: hair follicle dermal papilla Present 2b Day 5
TS28: hair outer root sheath Present 2b Day 5
TS28: hair root sheath matrix Present 2b Day 5
TS28: interfollicular epidermis Present Regionally restricted 2b Day 5 Expression is in the basal layer of the interfollicular epithelium.
Specimen 2b Day 12: postnatal day 12 (more )
Note: Follicles in catagen.
Structure Level Pattern Image Note
TS28: hair bulb Absent 2b Day 12
TS28: hair root sheath matrix Absent 2b Day 12
Specimen not shown P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: interfollicular epidermis Present Regionally restricted Expression is in the basal layer of the interfollicular epithelium.
Specimen not shown P18: postnatal day 18 (more )
Note: Follicles in catagen.
Structure Level Pattern Image Note
TS28: hair bulb Absent
TS28: interfollicular epidermis Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory