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Gene Expression Data
Assay Details
Assay
Reference: J:81603 Conway SJ, et al., Role of sodium-calcium exchanger (Ncx1) in embryonic heart development: a transgenic rescue?. Ann N Y Acad Sci. 2002 Nov;976:268-81
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7860768
Gene symbol: Slc8a1
Gene name: solute carrier family 8 (sodium/calcium exchanger), member 1
Reporter: lacZ
Direct Detection
Results
Specimen 1a: embryonic day 8.5; Slc8a1tm1Sjc/Slc8a1+ (more )
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 1a Expression is in cardiomyocytes and is absent in the rest of the embryo and extraembryonic tissues.
TS13: alimentary system Absent 1a
TS13: extraembryonic component Absent 1a
TS13: genitourinary system Absent 1a
TS13: neural ectoderm Absent 1a
TS13: non-neural ectoderm Absent 1a
TS13: sensory organ system Absent 1a
TS13: visceral organ system Absent 1a
Specimen 1b: postnatal newborn; Slc8a1tm1Sjc/Slc8a1+ (more )
Structure Level Pattern Image Note
TS27: heart Strong 1b
TS27: bladder Present 1b
TS27: brain Present 1b
TS27: metanephros Present 1b
TS27: spinal cord Present 1b
Specimen 1c: postnatal newborn; Slc8a1tm1Sjc/Slc8a1+ (more )
Structure Level Pattern Image Note
TS27: heart Strong 1c
TS27: spinal cord Present 1c
Specimen 1d: postnatal newborn; Slc8a1tm1Sjc/Slc8a1+ (more )
Structure Level Pattern Image Note
TS27: blood vessel smooth muscle Present Regionally restricted 1d
TS27: nerve Present Regionally restricted 1d
Specimen 1d inset: postnatal newborn; Slc8a1tm1Sjc/Slc8a1+ (more )
Structure Level Pattern Image Note
TS27: renal cortex Present 1d inset
TS27: renal medulla Absent 1d inset
Specimen 3a: embryonic day 14.0; Slc8a1tm1Sjc/Slc8a1+ (more )
Note: Double labeled: blue - Slc8a1 reporter; brown - Ncam1 (assay MGI:7860779).
Structure Level Pattern Image Note
TS22: heart Present Regionally restricted 3b , 3a Expression is in the subendocardial myocardial lining of the atrioventricular junction.
TS22: impulse conducting system Present Regionally restricted 3a , 3b Expression is in the atrioventricular node.
Specimen 4a: embryonic day 9.5; Slc8a1tm1Sjc/Slc8a1+ (more )
Structure Level Pattern Image Note
TS15: heart Present 4a
TS15: embryo Present Regionally restricted 4a Expression is in the heart and is absent anywhere else.
TS15: extraembryonic component Absent 4a
TS15: genitourinary system Absent 4a
TS15: head Absent 4a
TS15: hematopoietic system Absent 4a
TS15: limb Absent 4a
TS15: musculoskeletal system Absent 4a
TS15: nervous system Absent 4a
TS15: tail Absent 4a
Specimen 5 +/-: embryonic day 10.0; Slc8a1tm1Sjc/Slc8a1+ (more )
Structure Level Pattern Image Note
TS16: heart Present 5_+/-
Specimen 5 -/-: embryonic day 10.0; Slc8a1tm1Sjc/Slc8a1tm1Sjc (more )
Structure Level Pattern Image Note
TS16: heart Present 5_-/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory