Tg(Lep-luc)-0.762-13.6kRck
Transgene Detail
|
|
| Symbol: |
Tg(Lep-luc)-0.762-13.6kRck |
| Name: |
transgene insertion -0.762-13.6k, Jeffrey M Friedman |
| MGI ID: |
MGI:7859698 |
| Transgene: |
Tg(Lep-luc)-0.762-13.6kRck Location: unknown
|
| Alliance: |
Tg(Lep-luc)-0.762-13.6kRck page
|
|
|
|
| Transgene Type: |
|
Transgenic (Reporter) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The transgene insert consists of a modified BAC RP24-69D4 (GRCm39:chr6:29037900-29208588) where the ends were trimmed to chr6:29059436-29073901 and a luciferase reporter gene was inserted into the ATG start codon in exon 2 of the Lep gene. The modified BAC contains the Lep gene but lacks enhancers Rr603 (LE1, upstream) and Rr604 (LE2, downstream).
(J:310158)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:310158 Dallner OS, et al., Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity. Nat Med. 2019 Mar;25(3):507-516 |
| All: |
1 reference(s) |
|
Analysis Tools
