Tg(Lep-luc)-0.762-13.9kRck
Transgene Detail
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| Symbol: |
Tg(Lep-luc)-0.762-13.9kRck |
| Name: |
transgene insertion -0.762-13.9k, Jeffrey M Friedman |
| MGI ID: |
MGI:7859697 |
| Transgene: |
Tg(Lep-luc)-0.762-13.9kRck Location: unknown
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| Alliance: |
Tg(Lep-luc)-0.762-13.9kRck page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The transgene insert consists of a modified BAC RP24-69D4 (GRCm39:chr6:29037900-29208588) where the ends were trimmed to chr6:29059436-29074178 and a luciferase reporter gene was inserted into the ATG start codon in exon 2 of the Lep gene. The modified BAC contains the Lep gene and enhancer Rr604 (LE2, downstream), but lacks enhancer Rr603 (LE1, upstream).
(J:310158)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:310158 Dallner OS, et al., Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity. Nat Med. 2019 Mar;25(3):507-516 |
| All: |
1 reference(s) |
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Analysis Tools
