Gene Expression Data
Assay Details
Assay
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Reference:
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J:245876
Rohacek AM, et al., ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7857198
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Gene symbol:
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Bsnd
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Gene name:
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barttin CLCNK type accessory beta subunit
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Antibody:
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anti-Barttin
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Detection system:
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Secondary antibody coupled to Alexa Fluor 488
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Results
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Specimen
5J:
embryonic day 18.5
(more )
Specimen
5J:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5Q:
(close )
Genetic Background:
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involves: 129S4/SvJae * C57BL/6
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Mutant Allele(s):
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Esrp1tm1.2Rpc/Esrp1tm1.2Rpc
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: cochlea epithelium |
strial marginal cell |
Trace |
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5Q
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Expression reduced or absent compared to control.
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Specimen
7E:
embryonic day 18.5
(more )
Specimen
7E:
(close )
Genetic Background:
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Not Specified
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
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Specimen
7L:
(close )
Genetic Background:
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involves: 129S4/SvJae * C57BL/6
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Mutant Allele(s):
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Esrp1tm1.2Rpc/Esrp1tm1.2Rpc
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Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: cochlea epithelium |
strial marginal cell |
Trace |
|
7L
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Expression reduced or absent compared to control.
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Specimen
7S:
(close )
Genetic Background:
|
involves: 129S4/SvJae * C57BL/6
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Mutant Allele(s):
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Esrp1tm1.2Rpc/Esrp1tm1.2Rpc Fgf9tm1b(KOMP)Wtsi/Fgf9+
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Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: cochlea epithelium |
strial marginal cell |
Present |
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7S
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Authors report recovery of strial marginal cells.
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