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Gene Expression Data
Assay Details
Assay
Reference: J:245876 Rohacek AM, et al., ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7857196
Gene symbol: Esrrb
Gene name: estrogen related receptor, beta
Antibody: anti-Esrrb/Nr3b2
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5C: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: cochlea epithelium strial marginal cell Present 5C
Specimen 5F: embryonic day 16.5; Esrp1tm1.2Rpc/Esrp1tm1.2Rpc (more )
Structure Cell Type Level Pattern Image Note
TS24: cochlea epithelium strial marginal cell Trace 5F Dramatic reduction of strial marginal cells compared to control
Specimen 7C: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cochlea epithelium strial marginal cell Present 7C
Specimen 7J: embryonic day 18.5; Esrp1tm1.2Rpc/Esrp1tm1.2Rpc (more )
Structure Level Pattern Image Note
TS26: cochlea epithelium Trace 7J Dramatic reduction of strial marginal cellscompared to control
Specimen 7Q: embryonic day 18.5; Esrp1tm1.2Rpc/Esrp1tm1.2Rpc, Fgf9tm1b(KOMP)Wtsi/Fgf9+ (more )
Structure Level Pattern Image Note
TS26: cochlea epithelium Present 7Q Authors report recovery of strial marginal cell identity.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory