About   Help   FAQ
Tg(Vav1-BCL2A1)686Biat
Transgene Detail
Summary
Symbol: Tg(Vav1-BCL2A1)686Biat
Name: transgene insertion 686, Biomodels Austria
MGI ID: MGI:7857135
Transgene: Tg(Vav1-BCL2A1)686Biat  Location: unknown  
Alliance: Tg(Vav1-BCL2A1)686Biat page
Transgene
origin
Strain of Origin:  C57BL/6NCrl
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Vav1-BCL2A1)686Biat expresses 1 gene
 
Tg(Vav1-BCL2A1)686Biat expression driven by 1 gene
 
Mutation detailsThe Vav1 promoter drives expression of the human FLAG-BFL1 cDNA into C57BL/6N oocytes. The founder lines were designated as C57BL/6N-Tg(Vav-BFL1)676, 677, 686Biat, or shortly Vav-BFL1 TG line L1, L2, L3. (J:277367)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:277367 Tuzlak S, et al., Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis. FEBS J. 2018 Apr;285(8):1403-1418
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory