Tg(Vav1-BCL2A1)686Biat
Transgene Detail
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Symbol: |
Tg(Vav1-BCL2A1)686Biat |
Name: |
transgene insertion 686, Biomodels Austria |
MGI ID: |
MGI:7857135 |
Transgene: |
Tg(Vav1-BCL2A1)686Biat Location: unknown
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Alliance: |
Tg(Vav1-BCL2A1)686Biat page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Vav1-BCL2A1)686Biat expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
BCL2A1 (597) |
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Tg(Vav1-BCL2A1)686Biat expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Vav1 (MGI:98923) |
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Mutation details: The Vav1 promoter drives expression of the human FLAG-BFL1 cDNA into C57BL/6N oocytes. The founder lines were designated as C57BL/6N-Tg(Vav-BFL1)676, 677, 686Biat, or shortly Vav-BFL1 TG line L1, L2, L3.
(J:277367)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:277367 Tuzlak S, et al., Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis. FEBS J. 2018 Apr;285(8):1403-1418 |
All: |
1 reference(s) |
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