Gene Expression Data
Assay Details
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Assay
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Reference:
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J:149465
Holmes G, et al., Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology. Dev Biol. 2009 Apr 15;328(2):273-84
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7856743
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Gene symbol:
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Twist1
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Gene name:
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twist basic helix-loop-helix transcription factor 1
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Results
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Specimen
2D WT:
embryonic day 14.5
(more  )
Specimen
2D WT:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: chondrocranium |
Present |
Regionally restricted |
2D WT Twist1
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Expression in immature skeletal mesenchyme, the osteogenic fronts, and in sutural mesenchyme.
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Specimen
2D AP:
embryonic day 14.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
2D AP:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: chondrocranium |
Present |
Regionally restricted |
2D AP Twist1
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There are mild changes in expression in this mutant compared to controls.
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Specimen
not shown WT E15.5:
embryonic day 15.5
(more )
Specimen
not shown WT E15.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
|
|
Embedding:
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Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: chondrocranium |
Present |
Regionally restricted |
|
Expression in immature skeletal mesenchyme, the osteogenic fronts, and in sutural mesenchyme.
|
Specimen
not shown AP E15.5:
embryonic day 15.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
not shown AP E15.5:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
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Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: chondrocranium |
Present |
Regionally restricted |
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There are mild changes in expression in this mutant compared to controls.
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Analysis Tools
