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Gene Expression Data
Assay Details
Assay
Reference: J:262482 Dubos A, et al., A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Hum Mol Genet. 2018 Jun 15;27(12):2138-2153
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855743
Gene symbol: Calb2
Gene name: calbindin 2
Antibody: anti-Calretinin (MAB1568; clone 6B8.2)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen not shown Arxwt/0: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: amygdala Present
TS23: cerebral cortex Present
TS23: cerebral cortex intermediate zone Present
TS23: cerebral cortex marginal layer Present
TS23: cerebral cortex subventricular zone Present
TS23: corpus striatum Present
TS23: cortical plate Present
TS23: cortical subplate Present
TS23: hippocampus Present

Specimen not shown Arxdup24/0: embryonic day 15.5; Arxtm1.1Ics/Y (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present The number of positive cells in this structure is the same as in wild-type.
TS23: hippocampus Present The number of positive cells in this structure is the same as in wild-type.
TS23: amygdala Present The number of positive cells in this structure had decreased compared to wild-type.
TS23: cerebral cortex Present The number of positive cells in this structure had decreased compared to wild-type.
TS23: cerebral cortex intermediate zone Present The number of positive cells in this structure had decreased compared to wild-type.
TS23: cerebral cortex subventricular zone Present The number of positive cells in this structure had decreased compared to wild-type.
TS23: corpus striatum Present The number of positive cells in this structure had decreased compared to wild-type.
TS23: cortical plate Present The number of positive cells in this structure had decreased compared to wild-type.
TS23: cortical subplate Present The number of positive cells in this structure had decreased compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory