Gene Expression Data
Assay Details
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Assay
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Reference:
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J:262482
Dubos A, et al., A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Hum Mol Genet. 2018 Jun 15;27(12):2138-2153
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7855696
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Gene symbol:
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Arx
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Gene name:
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aristaless related homeobox
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Antibody:
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anti-ARX-Cter
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
S2G:
embryonic day 15.5
(more  )
Specimen
S2G:
(close  )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * C57BL/6N
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Age:
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embryonic day 15.5
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
S2H:
embryonic day 15.5; Arxtm1.1Ics/Y
(more )
Specimen
S2H:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Arxtm1.1Ics/Y
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Age:
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embryonic day 15.5
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown Arxwt/0 P0:
postnatal day 0
(more )
Specimen
not shown Arx P0:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * C57BL/6N
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Age:
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postnatal day 0
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown Arxdup24/0 P0:
postnatal day 0; Arxtm1.1Ics/Y
(more )
Specimen
not shown Arx P0:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Arxtm1.1Ics/Y
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Age:
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postnatal day 0
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cerebral cortex |
Present |
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Although there was no major difference between the number of positive cells in the cortex of this mutant, the distribution was slightly different.
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Specimen
not shown Arxwt/0 Adult:
postnatal adult
(more )
Specimen
not shown Arx Adult:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * C57BL/6N
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Age:
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postnatal adult
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown Arxdup24/0 Adult:
postnatal adult; Arxtm1.1Ics/Y
(more )
Specimen
not shown Arx Adult:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Arxtm1.1Ics/Y
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Age:
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postnatal adult
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
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There were slight differences in distribution of positive cells compared to wild-type.
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Analysis Tools