Tg(CAG-Arl13b/GFP)1Tc
Transgene Detail
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| Symbol: |
Tg(CAG-Arl13b/GFP)1Tc |
| Name: |
transgene insertion 1, Tamara Caspary |
| MGI ID: |
MGI:7855567 |
| Synonyms: |
CAGGS-Arl13bGFP |
| Transgene: |
Tg(CAG-Arl13b/GFP)1Tc Location: unknown
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| Alliance: |
Tg(CAG-Arl13b/GFP)1Tc page
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| Strain of Origin: |
Not Applicable
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: GFP is fused to Arl13b cDNA and put under the control of pCAGGS promoter expression. Four different founder lines (each obtained from a different pronuclear injection) were generated and all were confirmed to specifically express GFP in cilia, while no GFP could be seen in other cell organelles. Only the one line that expresses the highest level of GFP was maintained. The pCAGGS promoter was chosen because it can drive the strong and ubiquitous expression of the Arl13b-GFP fusion protein.
(J:206912)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:206912 Larkins CE, et al., Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins. Mol Biol Cell. 2011 Dec;22(23):4694-703 |
| All: |
1 reference(s) |
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Analysis Tools
