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Gene Expression Data
Assay Details
Assay
Reference: J:123923 Zhou Q, et al., A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell. 2007 Jul;13(1):103-14
Assay type: RNA in situ
MGI Accession ID: MGI:7852679
Gene symbol: Ptf1a
Gene name: pancreas specific transcription factor, 1a
Probe: MTF#1208
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: There were multiple possible probes that could have been used for this assay: MGI:4879166, MGI:4879353.
Results
Specimen 2B: embryonic day 14.5 (more )
Note: Double labeled: purple - Ptf1a; reddish brown - Amy (assay MGI:7852792).
Structure Cell Type Level Pattern Image Note
TS22: pancreas branching epithelium tip pancreas exocrine glandular cell Present 2B Expression overlaps completely with the exocrine cell marker Amylase (Amy) staining.
Specimen 2F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pancreas branching epithelium tip Weak 2F
Specimen Table S1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas branching epithelium tip Present Regionally restricted Expression was confined to the distal tips of the pancreatic epithelial tree.
Specimen S5B: embryonic day 12.5 (more )
Note: Double labeled: purple - Ptf1a; reddish brown - Cpa1 (assay MGI:7852795).
Structure Level Pattern Image Note
TS20: pancreas branching epithelium tip Weak Regionally restricted S5B Weak expression was detected in the newly formed branches of the dorsal pancreas at E12.5, where it co-expressed Cpa1. Expression was downregulated in the 'cleft' region between future branches.
Specimen wholemount screen: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas branching epithelium tip Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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