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Gene Expression Data
Assay Details
Assay
Reference: J:122415 Michalski N, et al., Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning. J Neurosci. 2007 Jun 13;27(24):6478-88
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7852212
Gene symbol: Ush2a
Gene name: usherin
Antibody: U2aCyt1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: postnatal day 6 (more )
Note: Double labeled: green - Ush2a; red - Actin.
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 3A Expression is at the base of stereocilia and along the kinocilium.
Specimen 3A': postnatal day 6; Adgrv1tm1Msat/Adgrv1tm1Msat (more )
Note: Double labeled: green - Ush2a; red - Actin.
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 3A' Expression is absent at the base of the hair bundle but remains in the kinocilium in both outer and inner hair cells.
Specimen 4B: postnatal day 6 (more )
Note: Double labeled: green - Ush2a; red - Actin.
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 4B Expression is at the base of stereocilia and along the kinocilium.
Specimen 4B': postnatal day 6; Myo7a4626SB/Myo7a4626SB (more )
Note: Double labeled: green - Ush2a; red - Actin.
Structure Level Pattern Image Note
TS28: organ of Corti Trace Regionally restricted 4B' Expression is beneath the apical cell surface of inner hair cells.
Specimen 4B'': postnatal day 6; Whrnwi/Whrnwi (more )
Note: Double labeled: green - Ush2a; red - Actin.
Structure Level Pattern Image Note
TS28: organ of Corti Absent 4B''
Specimen S1B: postnatal day 7 (more )
Note: Triple labeled: green - Ush2a; blue - Adgrv1 (assay MGI:7852160); red - Actin.
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S1D , S1B Expression is in a tight band at the base of stereocilia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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