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Gene Expression Data
Assay Details
Assay
Reference: J:174826 Rousselet E, et al., PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res. 2011 Jul;52(7):1383-91
Assay type: Western blot
MGI Accession ID: MGI:7852181
Gene symbol: Apoe
Gene name: apolipoprotein E
Antibody: anti-apoE
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure 34 kDa (a) 28 kDa (b) Genetic BackgroundMutant Allele(s)Sex
WT 1 P adult TS28: main olfactory bulb Present Present C57BL/6J Not Specified
WT 2 P adult TS28: main olfactory bulb Present Present C57BL/6J Not Specified
WT 3 P adult TS28: main olfactory bulb Present Present C57BL/6J Not Specified
WT 4 P adult TS28: main olfactory bulb Present Present C57BL/6J Not Specified
Pcsk9-/- 1 P adult TS28: main olfactory bulb Present (c) Present (c) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Pcsk9-/- 2 P adult TS28: main olfactory bulb Present (c) Present (c) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Pcsk9-/- 3 P adult TS28: main olfactory bulb Present (c) Present (c) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Pcsk9-/- 4 P adult TS28: main olfactory bulb Present (c) Present (c) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Notes:
(a) nontruncated form
(b) truncated form
(c) Similar as the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory