Pcsk9 RNA in situ Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:174826 Rousselet E, et al., PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res. 2011 Jul;52(7):1383-91
Assay type:	RNA in situ
MGI Accession ID:	MGI:7850833
Gene symbol:	Pcsk9
Gene name:	proprotein convertase subtilisin/kexin type 9

Probe:	NARC-1 cDNA
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

1A PCSK9 ©

Specimen 1A: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: liver	Present		1A PCSK9
TS20: small intestine	Present		1A PCSK9
TS20: neocortex	Present	Regionally restricted	1A PCSK9	Expressed in the frontal cortex.

2A PCSK9 ©

Specimen 2A: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum external granule cell layer	Present		2A PCSK9

3A PCSK9 ©

Specimen 3A: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: olfactory tract	Present	Regionally restricted	3A PCSK9	Expressed in the rostral extension of the olfactory peduncle.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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