Tg(CAG-LacZ,-ACVR1*,-EGFP)A11Mis
Transgene Detail
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Symbol: |
Tg(CAG-LacZ,-ACVR1*,-EGFP)A11Mis |
Name: |
transgene insertion A11, Yuji Mishina |
MGI ID: |
MGI:7840390 |
Synonyms: |
Tg(CAG-LacZ,-ACVR1*,-EGFP)2Mis |
Transgene: |
Tg(CAG-LacZ,-ACVR1*,-EGFP)A11Mis Location: unknown
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Alliance: |
Tg(CAG-LacZ,-ACVR1*,-EGFP)A11Mis page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: The modified chicken beta-actin promoter (CAG) was used to drive ubiquitous expression of a floxed LacZ gene with a triple polyadenylation signal sequence followed by a constitutively active human ACVR1 sequence with the amino acid substitution of glutamine with aspartic acid at position 207 (Q207D), an IRES sequence, and the EGFP coding sequence and a poly(A) signal.
(J:304330)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:304330 Yang J, et al., Generation of a new mouse line with conditionally activated signaling through the BMP receptor, ACVR1: A tool to characterize pleiotropic roles of BMP functions. Genesis. 2021 Apr 14;:e23419 |
All: |
2 reference(s) |
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