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Gene Expression Data
Assay Details
Assay
Reference: J:174095 Cai Z, et al., Loss of shp2-mediated mitogen-activated protein kinase signaling in muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul;31(14):2973-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7788891
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Results
Specimen S2A: embryonic day 16.0 (more )
Note: Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS24: retina layer Present Regionally restricted S2A Expressed in the outer layers.

Specimen S2B: embryonic day 16.0; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS24: retina layer Present Regionally restricted S2B Expressed in the outer layers, similar as in the wild-type.

Specimen S2C: postnatal day 0 (more )
Note: Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS27: retina layer Present Regionally restricted S2C Expressed in the neuroblastic layer.

Specimen S2D: postnatal day 0; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS27: retina layer Present Regionally restricted S2D Expressed in the neuroblastic layer, similar as in the wild-type.

Specimen S2E: postnatal day 3 (more )
Note: Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS27: retina layer Present Regionally restricted S2E Expressed in the neuroblastic layer.
TS27: retina outer nuclear layer Present S2E

Specimen S2F: postnatal day 3; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS27: retina layer Present Regionally restricted S2F Expressed in the neuroblastic layer, similar as in the wild-type.
TS27: retina outer nuclear layer Present S2F Similar as in the wild-type.

Specimen S2G: postnatal day 7 (more )
Note: Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2G

Specimen S2H: postnatal day 7; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2H Same as in the wild-type.

Specimen S2I: postnatal day 10 (more )
Note: Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2I

Specimen S2J: postnatal day 10; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2J Same as in the wild-type.

Specimen S2K: postnatal day 14 (more )
Note: Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2K

Specimen S2L: postnatal day 14; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2L Same as in the wild-type.

Specimen S2M: postnatal day 21 (more )
Note: Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2M

Specimen S2N: postnatal day 21; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Mki67; green - pHH3.
Structure Level Pattern Image Note
TS28: retina Absent S2N Same as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory