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Gene Expression Data
Assay Details
Assay
Reference: J:214972 Fei D, et al., The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development. Neural Dev. 2014;9:15
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7786619
Gene symbol: P2rx3
Gene name: purinergic receptor P2X, ligand-gated ion channel, 3
Antibody: anti-P2X3 (AB5895)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 6A: postnatal (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS28: nerve Present Regionally restricted 6A Expression is in the innervation of the taste bud.
TS28: taste bud Present Regionally restricted 6A Expression is in the innervation of the taste bud.
Specimen 6B: postnatal; Ngfrtm1Jae/Ngfrtm1Jae (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS28: nerve Present Regionally restricted 6B This mutant only has 80% of taste buds innervated compared to wild-type.
TS28: taste bud Present Regionally restricted 6B This mutant only has 80% of taste buds innervated compared to wild-type.
Specimen 6C: postnatal; Ngfrtm1Jae/Ngfrtm1Jae (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS28: nerve Present Regionally restricted 6C This mutant only has 80% of taste buds innervated compared to wild-type.
TS28: taste bud Present Regionally restricted 6C This mutant only has 80% of taste buds innervated compared to wild-type.
Specimen 7A: postnatal newborn; Ngfrtm1Jae/Ngfrtm1Jae (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS27: nerve Present Regionally restricted 7A In this mutant there were both stained and unstained taste buds.
TS27: taste bud Present Regionally restricted 7A In this mutant there were both stained and unstained taste buds.
Specimen 7B: postnatal newborn; Ngfrtm1Jae/Ngfrtm1Jae, Ntrk2tm1Bbd/Ntrk2tm1Bbd (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS27: nerve Present Regionally restricted 7B Most of the taste buds were unstained.
TS27: taste bud Present Regionally restricted 7B Most of the taste buds were unstained.
Specimen 7C: postnatal newborn; Ngfrtm1Jae/Ngfrtm1Jae (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS27: nerve Present 7C In this mutant there were both stained and unstained taste buds.
TS27: taste bud Present 7C In this mutant there were both stained and unstained taste buds.
Specimen 7D: postnatal newborn; Ngfrtm1Jae/Ngfrtm1Jae (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS27: nerve Present 7D In this mutant there were both stained and unstained taste buds.
TS27: taste bud Present 7D In this mutant there were both stained and unstained taste buds.
Specimen 7E: postnatal newborn; Ngfrtm1Jae/Ngfrtm1Jae, Ntrk2tm1Bbd/Ntrk2tm1Bbd (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS27: nerve Present Regionally restricted 7E Most of the taste buds were unstained.
TS27: taste bud Present Regionally restricted 7E Most of the taste buds were unstained.
Specimen 7F: postnatal newborn; Ngfrtm1Jae/Ngfrtm1Jae, Ntrk2tm1Bbd/Ntrk2tm1Bbd (more )
Note: Double labeled: red - P2rx3; green - Krt8 (assay MGI:7786617).
Structure Level Pattern Image Note
TS27: nerve Present Regionally restricted 7F Most of the taste buds were unstained.
TS27: taste bud Present Regionally restricted 7F Most of the taste buds were unstained.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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