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Gene Expression Data
Assay Details
Assay
Reference: J:117240 Netzel-Arnett S, et al., Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation. J Biol Chem. 2006 Nov 3;281(44):32941-5
Assay type: Western blot
MGI Accession ID: MGI:7779950
Gene symbol: Prss8
Gene name: serine protease 8 (prostasin)
Results
Image: 3A ©

 Sample Information Bands Other Sample Information
Lane AgeStructure 39 kDa (a) 37 kDa (b) Genetic BackgroundMutant Allele(s)Sex
Pl-PLC Cultured cells: no data stored
Cell lysate Cultured cells: no data stored
Matriptase + P newborn TS27: epidermis Present Present (c) involves: 129P2/OlaHsd Not Specified
Matriptase + P newborn TS27: epidermis Present Present (c) involves: 129P2/OlaHsd Not Specified
Matriptase + P newborn TS27: epidermis Present Present (c) involves: 129P2/OlaHsd Not Specified
Matriptase - P newborn TS27: epidermis Present (d) Absent (e) involves: 129P2/OlaHsd St14tm1Bug/St14tm1BugNot Specified
Matriptase - P newborn TS27: epidermis Present (d) Absent (e) involves: 129P2/OlaHsd St14tm1Bug/St14tm1BugNot Specified
Matriptase - P newborn TS27: epidermis Present (d) Absent (e) involves: 129P2/OlaHsd St14tm1Bug/St14tm1BugNot Specified
Notes:
(a) prostasin zymogen
(b) activated prostasin
(c) 40-51% of prostasin was in the active two-chain form.
(d) Prostasin was exclusively found in the higher molecular mass 39-kDa zymogen form, which was frequently more abundant in matriptase-deficient epidermis.
(e) below the level of detection
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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