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Gene Expression Data
Assay Details
Assay
Reference: J:173598 Jacquet BV, et al., Specification of a Foxj1-Dependent Lineage in the Forebrain Is Required for Embryonic-to-Postnatal Transition of Neurogenesis in the Olfactory Bulb. J Neurosci. 2011 Jun 22;31(25):9368-82
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7764111
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 8B WT OVZ: postnatal day 0; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(FOXJ1-cre)F26Htzm/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; blue - Foxj1 (assay MGI:7764110); red - Cre reporter.
Structure Level Pattern Image Note
TS27: main olfactory bulb ventricular layer Present 8B WT left , 8B WT middle Foxj1+/Mki67+ cycling cells were extended into the olfactory ventricular zone. The levels of tdTomato expression were significantly lower in Foxj1+ progenitors than in their migrating progeny.
TS27: lateral ganglionic eminence Present Regionally restricted 8B WT left Foxj1+/Mki67+ cycling cells were found within the dorsolateral wall.
Specimen 8B KO OVZ: postnatal day 0; Foxj1tm1Slb/Foxj1tm1Slb, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(FOXJ1-cre)F26Htzm/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; blue - Foxj1 (assay MGI:7764110); red - Cre reporter.
Structure Level Pattern Image Note
TS27: main olfactory bulb ventricular layer Present 8B KO middle , 8B KO left Proliferating tdTomato+ cells were nearly depleted.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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