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Gene Expression Data
Assay Details
Assay
Reference: J:74989 McEvilly RJ, et al., Transcriptional regulation of cortical neuron migration by POU domain factors. Science. 2002 Feb 22;295(5559):1528-32
Assay type: RNA in situ
MGI Accession ID: MGI:7751273
Gene symbol: Cdk5r1
Gene name: cyclin dependent kinase 5, regulatory subunit 1
Results
Specimen 4A p35 (upper) WT: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present 4A p35 (upper) WT

Specimen 4A p35 (upper) Brn-1-/-: embryonic day 18.0; Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Weak 4A p35 (upper) Brn-1-/- Expression markedly decreased compared to wild type.

Specimen 4A p35 (upper) Brn-1-/-/Brn-2-/-: embryonic day 18.0; Pou3f2tm1Rsd/Pou3f2tm1Rsd, Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Trace 4A p35 (upper) Brn-1-/-/Brn-2-/- Expression nearly absent.

Specimen 4A p35 (lower) WT: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: hippocampus CA1 Present 4A p35 (lower) WT
TS26: hippocampus CA3 Present 4A p35 (lower) WT

Specimen 4A p35 (lower) Brn-1-/-: embryonic day 18.0; Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS26: hippocampus CA1 Trace 4A p35 (lower) Brn-1-/- Expression nearly absent.
TS26: hippocampus CA3 Present 4A p35 (lower) Brn-1-/-

Specimen 4A p35 (lower) Brn-1-/-/Brn-2-/-: embryonic day 18.0; Pou3f2tm1Rsd/Pou3f2tm1Rsd, Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS26: hippocampus CA1 Trace 4A p35 (lower) Brn-1-/-/Brn-2-/- Expression nearly absent.
TS26: hippocampus CA3 Present 4A p35 (lower) Brn-1-/-/Brn-2-/-

Specimen S4B p35 WT: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: main olfactory bulb mitral cell layer mitral cell Present S4B p35 WT

Specimen S4B p35 Brn-1-/-/Brn-2-/-: embryonic day 18.0; Pou3f2tm1Rsd/Pou3f2tm1Rsd, Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb mitral cell layer Absent S4B p35 Brn-1-/-/Brn-2-/- Expression reduced to background levels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory