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Gene Expression Data
Assay Details
Assay
Reference: J:171452 Holtz ML, et al., Serum response factor is required for cell contact maintenance but dispensable for proliferation in visceral yolk sac endothelium. BMC Dev Biol. 2011;11:18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7750939
Gene symbol: Vcl
Gene name: vinculin
Results
Specimen 4A: embryonic day 12.5 (more )
Note: Fixed in zinc fixative or zinc formalin. Double labeled: red - Vcl; green - Srf (assay MGI:7750935).
Structure Level Pattern Image Note
TS20: yolk sac mesenchyme Present 4A

Specimen 4B: embryonic day 12.5; Srftm1Rmn/Srftm1Rmn, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Fixed in zinc fixative or zinc formalin. Double labeled: red - Vcl; green - Srf (assay MGI:7750935).
Structure Level Pattern Image Note
TS20: yolk sac mesenchyme Present 4B Expression was moderately disrupted in the mutant compared to the wild-type. Disturbance was correlated with loss of Srf protein.

Specimen 4C: embryonic day 10.5 (more )
Note: Fixed in zinc fixative or zinc formalin.
Structure Level Pattern Image Note
TS17: yolk sac mesenchyme Present 4C

Specimen 4D: embryonic day 10.5; Srftm1Rmn/Srftm1Rmn, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Fixed in zinc fixative or zinc formalin.
Structure Level Pattern Image Note
TS17: yolk sac mesenchyme Present 4D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory