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Gene Expression Data
Assay Details
Assay
Reference: J:78912 Hellstrom M, et al., Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7750907
Gene symbol: Tjp1
Gene name: tight junction protein 1
Antibody: anti-ZO-1
Results
Specimen 7g: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain vascular element Present Regionally restricted 7g Expression confined to junctions.
Specimen 7h: embryonic day 18.5; Pdgfrbtm1Sor/Pdgfrbtm1Sor (more )
Structure Level Pattern Image Note
TS26: brain vascular element Present Regionally restricted 7h No difference in junctional localization or intensity of expression compared to wild type.
Specimen 7i: embryonic day 18.5; Pdgfrbtm1Sor/Pdgfrbtm1Sor (more )
Note: Double labeled: red - Tjp1; green - Fn1 (assay MGI:7750903).
Structure Level Pattern Image Note
TS26: brain vascular element Present Regionally restricted 7i Authors report a highly irregular endothelial organization.
Specimen E12.5 wild type not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present
Specimen E12.5 knock out not shown: embryonic day 12.5; Pdgfrbtm1Sor/Pdgfrbtm1Sor (more )
Structure Level Pattern Image Note
TS20: brain Present No difference in junctional localization or intensity of expression compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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