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Gene Expression Data
Assay Details
Assay
Reference: J:235368 Gomez-Del Arco P, et al., The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis. Cell Metab. 2016 May 10;23(5):881-92
Assay type: RNA in situ
MGI Accession ID: MGI:7750770
Gene symbol: Mycn
Gene name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Probe: Mycn probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S1D WT: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: heart septum Present Regionally restricted S1D WT bottom Expression of the proliferation marker Mycn was detected in the interventricular septum.
TS17: cardiac muscle tissue fetal cardiomyocyte Present Regionally restricted S1D WT bottom Expression was detected in the proliferating cardiomyocytes in the compact myocardium.
Specimen S1D Chd4nkx: embryonic day 10.5; Chd4tm1.1Kge/Chd4tm1.1Kge, Nkx2-5tm2(cre)Rph/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: heart septum Weak Regionally restricted S1D Chd4nkx bottom Expression of the proliferation marker Mycn was lower in the interventricular septum of the mutant compared with wild type.
TS17: cardiac muscle tissue fetal cardiomyocyte Weak Regionally restricted S1D Chd4nkx bottom Less expression was detected in the proliferating cardiomyocytes in the compact myocardium of the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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