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Gene Expression Data
Assay Details
Assay
Reference: J:354690 Skelin L, et al., Connexin Expression Is Altered in the Eye Development of Yotari Mice: A Preliminary Study. Biomolecules. 2024 Sep 19;14(9)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7738439
Gene symbol: Gja5
Gene name: gap junction protein, alpha 5
Antibody: anti-Cx40/GJA5 (ab213688)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5a: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: eye muscle Present 5a MERGED , 5a Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS21: optic choroid Present 5a MERGED , 5a Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS21: neural retina Strong Regionally restricted 5a Cx40 , 5a MERGED Higher intensity of expression in basal region compared to mutant.

Specimen 5b: embryonic day 13.5; Dab1yot/Dab1yot (more )
Structure Level Pattern Image Note
TS21: eye muscle Present 5b MERGED , 5b Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS21: neural retina Present 5b MERGED , 5b Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS21: optic choroid Present 5b MERGED , 5b Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.

Specimen 5c: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: eye muscle Present 5c MERGED , 5c Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS23: neural retina Present 5c MERGED , 5c Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS23: optic choroid Present 5c MERGED , 5c Cx40 Most of expression localized in retinal apical and basal layers, choroid and muscles.

Specimen 5d: embryonic day 15.5; Dab1yot/Dab1yot (more )
Structure Level Pattern Image Note
TS23: eye muscle Present 5d Cx40 , 5d MERGED Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS23: optic choroid Present 5d Cx40 , 5d MERGED Most of expression localized in retinal apical and basal layers, choroid and muscles.
TS23: neural retina Strong Regionally restricted 5d MERGED , 5d Cx40 Stronger intensity of expression in apical retinal layer compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory