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Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: RNA in situ
MGI Accession ID: MGI:7738295
Gene symbol: Arx
Gene name: aristaless related homeobox
Probe: Arx cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S6A: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex intermediate zone cortical interneuron Present S6A
TS20: cerebral cortex marginal layer cortical interneuron Present S6A
TS20: cerebral cortex subventricular zone cortical interneuron Present S6A
TS20: telencephalon interneuron Present Regionally restricted S6A Expression was detected in the subpallium interneurons.

Specimen S6B: embryonic day 12.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS20: pallium cortical interneuron Present Single cells S6B Expression was scarce in the miR-9-2/3 double mutant pallium, but apparently normal in the miR-9-2/3 double mutant subpallium, suggesting that interneurons were generated, but their migration was impaired in the miR-9-2/3 double mutants.
TS20: telencephalon interneuron Present Regionally restricted S6B Expression was scarce in the miR-9-2/3 double mutant pallium, but apparently normal in the miR-9-2/3 double mutant subpallium, suggesting that interneurons were generated, but their migration was impaired in the miR-9-2/3 double mutants.

Specimen S6C: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex intermediate zone cortical interneuron Present S6C
TS21: cerebral cortex marginal layer cortical interneuron Present S6C
TS21: cerebral cortex subventricular zone cortical interneuron Present S6C
TS21: telencephalon interneuron Present Regionally restricted S6C Expression was detected in the subpallium interneurons.

Specimen S6D: embryonic day 13.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS21: pallium cortical interneuron Present Single cells S6D Expression was scarce in the miR-9-2/3 double mutant pallium, but apparently normal in the miR-9-2/3 double mutant subpallium, suggesting that interneurons were generated, but their migration was impaired in the miR-9-2/3 double mutants.
TS21: telencephalon interneuron Present Regionally restricted S6D Expression was scarce in the miR-9-2/3 double mutant pallium, but apparently normal in the miR-9-2/3 double mutant subpallium, suggesting that interneurons were generated, but their migration was impaired in the miR-9-2/3 double mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory