Gene Expression Data
Assay Details
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Assay
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Reference:
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J:76411
Lim L, et al., Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele. Am J Physiol Lung Cell Mol Physiol. 2002 May;282(5):L1012-22
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7738188
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Gene symbol:
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Ptch1
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Gene name:
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patched 1
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Probe:
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Ptc probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
6B wt:
embryonic day 11.0
(more  )
Specimen
6B wt:
(close  )
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Genetic Background:
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involves: CD-1
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: lung mesenchyme |
Present |
Regionally restricted |
6B wt
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Expression overlapping with Foxf1 in distal mesenchymal cells.
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Specimen
6B ht:
embryonic day 11.0; Foxf1tm1Rhc/Foxf1 +
(more )
Specimen
6B ht:
(close )
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Genetic Background:
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involves: 129P3/J * Black Swiss * CD-1
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Mutant Allele(s):
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Foxf1tm1Rhc/Foxf1+
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: lung mesenchyme |
Present |
Regionally restricted |
6B ht
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Expression in fewer distal mesenchyme regions compared to wild type.
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Specimen
7B wt:
embryonic day 12.0
(more )
Specimen
7B wt:
(close )
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Genetic Background:
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involves: CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
7B ht:
embryonic day 12.0; Foxf1tm1Rhc/Foxf1 +
(more )
Specimen
7B ht:
(close )
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Genetic Background:
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involves: 129P3/J * Black Swiss * CD-1
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Mutant Allele(s):
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Foxf1tm1Rhc/Foxf1+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: lung mesenchyme |
Present |
Regionally restricted |
7B ht
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Authors report decreased number of mesenchyma-epithelial interfaces, consistent with branching abnormalizy.
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Analysis Tools
