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Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736769
Gene symbol: L1cam
Gene name: L1 cell adhesion molecule
Antibody: anti-L1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 8G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus callosum Present 8G
TS26: hippocampal commissure Present 8G

Specimen 8H: embryonic day 18.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS26: corpus callosum Present 8H The corpus callosum and hippocampal commissure labeled by L1 were poorly formed.
TS26: hippocampal commissure Present 8H The corpus callosum and hippocampal commissure labeled by L1 were poorly formed.

Specimen 10A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain fiber tract Present Regionally restricted 10A , 10A' Expression was detected in the corticofugal axons and thalamocortical axons.
TS26: thalamocortical tract Present Regionally restricted 10A , 10A' Expression was detected in the corticofugal axons and thalamocortical axons.

Specimen 10B: embryonic day 18.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS26: brain fiber tract Present Regionally restricted 10B , 10B' Expression was detected in the corticofugal axons and thalamocortical axons. Corticofugal axons poorly innervated the internal capsule, and thalamocortical axons were nearly lost before reaching the internal capsule. A majority of the fibers abnormally descended into the hypothalamus.
TS26: thalamocortical tract Present Regionally restricted 10B , 10B' Expression was detected in the corticofugal axons and thalamocortical axons. Corticofugal axons poorly innervated the internal capsule, and thalamocortical axons were nearly lost before reaching the internal capsule. A majority of the fibers abnormally descended into the hypothalamus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory