About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736767
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Antibody: Anti-Ctip2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 8A miR-9-2 +/+; miR9-3 +/+: embryonic day 18.5 (more )
Note: Double labeled: green - Bcl11b; red - Sox5 (assay MGI:7736768).
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex motor neuron Present Regionally restricted 8A top Ctip2 , 8A top merged Ctip2 marks corticospinal motor neurons.
Specimen 8A miR-9-2 -/-; miR9-3 -/-: embryonic day 18.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Note: Double labeled: green - Bcl11b; red - Sox5 (assay MGI:7736768).
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex motor neuron Present Regionally restricted 8A bottom merged , 8A bottom Ctip2 Ctip2 expression was expanded into deeper layers in miR-9-2/3 double mutants.
Specimen 9C': embryonic day 18.5 (more )
Note: Double labeled: green - Bcl11b; red - Pou3f2 (assay MGI:7737645).
Structure Cell Type Level Pattern Image Note
TS26: corpus striatum striatum neuron Present Regionally restricted 9C' , 9C''' , 9C'' Expression was detected in the differentiating field.
Specimen 9D': embryonic day 18.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Note: Double labeled: green - Bcl11b; red - Pou3f2 (assay MGI:7737645).
Structure Cell Type Level Pattern Image Note
TS26: corpus striatum striatum neuron Weak Regionally restricted 9D''' , 9D' , 9D'' Expression in the differentiating field was greatly reduced.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory