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Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: RNA in situ
MGI Accession ID: MGI:7736765
Gene symbol: Etv1
Gene name: ets variant 1
Probe: Er81 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 8A miR-9-2 +/+; miR9-3 +/+: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex cerebral cortex neuron Present Regionally restricted 8A top Er81 Expression was detected in all layer V neurons.
Specimen 8A miR-9-2 -/-; miR9-3 -/-: embryonic day 18.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex cerebral cortex neuron Weak Regionally restricted 8A bottom Er81 Expression was reduced in layer V neurons.
Specimen 8C miR-9-2 +/+; miR9-3 +/+: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex cerebral cortex neuron Present Regionally restricted 8C Er81 left Expression was detected in all layer V neurons.
Specimen 8C miR-9-2 -/-; miR9-3 -/-: embryonic day 18.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex cerebral cortex neuron Weak Regionally restricted 8C Er81 right Expression was reduced in layer V neurons.
Specimen S4B miR-9-2 +/+; miR9-3 +/+: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted S4B Er81 top Expression was detected in layer V.
Specimen S4B miR-9-2 -/-; miR9-3 +/+: embryonic day 16.5; Mir9-2tm1Sia/Mir9-2tm1Sia (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted S4B Er81 bottom Single homozygous mutants didn't exhibit any apparent defects in neurogenesis.
Specimen S6M: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: lateral ganglionic eminence interneuron Present Regionally restricted S6M Interneurons generated in the lateral ganglionic eminence migrated to the olfactory bulb via the rostral migratory stream.
TS24: rostral migratory stream interneuron Present Regionally restricted S6M Interneurons generated in the lateral ganglionic eminence migrated to the olfactory bulb via the rostral migratory stream.
Specimen S6N: embryonic day 16.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS24: lateral ganglionic eminence interneuron Present S6N Interneurons in the rostral migratory stream to the olfactory bulb were also generated apparently normally in the miR-9-2/3 double-mutant lateral ganglionic eminence.
TS24: rostral migratory stream interneuron Present S6N Interneurons in the rostral migratory stream to the olfactory bulb were also generated apparently normally in the miR-9-2/3 double-mutant lateral ganglionic eminence.
Specimen S8G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: amygdala Present Regionally restricted S8G Expression was detected in the basolateral amygdala.
Specimen S8H: embryonic day 18.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS26: telencephalon Present Regionally restricted S8H The Etv1-positive basolateral amygdala was lost in the double mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory