Gene Expression Data
Assay Details
Assay
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Reference:
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J:89119
Jones L, et al., Pax6 is required for the normal development of the forebrain axonal connections. Development. 2002 Nov;129(21):5041-52
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7736630
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Gene symbol:
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Cntn2
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Gene name:
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contactin 2
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Antibody:
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anti-TAG1
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
5M/N:
embryonic day 14.5
(more )
Specimen
5M/N:
(close )
Genetic Background:
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involves: C57BL/6J * DBA/2J * NMRI
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Agarose
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Structure |
Level |
Pattern |
Image |
Note |
TS22: forebrain |
Present |
Regionally restricted |
5N
,
5M
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Expression in corticofugal axons extending throught intermediate zone of developing pallium to reach the pallial/subpallial boundary.
|
Specimen
5O/P:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Agarose
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: forebrain |
Present |
Regionally restricted |
5P
,
5O
|
Expression in corticofugal axons with abnormal trajectories, displaced laterally in thick bundles, that do not cross pallial/subpallial boundary.
|
Specimen
E18.5 wild-type not shown:
embryonic day 18.5
(more )
Specimen
E18.5 wild-type not shown:
(close )
Genetic Background:
|
involves: C57BL/6J * DBA/2J * NMRI
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Agarose
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: corpus callosum |
Present |
|
|
Expression primarily in cells of cortical plate and marginal zone in hippocampus and corpus callosum.
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TS26: cortical plate |
Present |
|
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Expression primarily in cells of cortical plate and marginal zone in hippocampus and corpus callosum.
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TS26: hippocampus marginal layer |
Present |
|
|
Expression primarily in cells of cortical plate and marginal zone in hippocampus and corpus callosum.
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Specimen
E18.5 Pax6-/- not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
|
Mutant Allele(s):
|
Pax6tm1Pgr/Pax6tm1Pgr
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Agarose
|
|