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Gene Expression Data
Assay Details
Assay
Reference: J:89119 Jones L, et al., Pax6 is required for the normal development of the forebrain axonal connections. Development. 2002 Nov;129(21):5041-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736630
Gene symbol: Cntn2
Gene name: contactin 2
Antibody: anti-TAG1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 5M/N: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present Regionally restricted 5N , 5M Expression in corticofugal axons extending throught intermediate zone of developing pallium to reach the pallial/subpallial boundary.

Specimen 5O/P: embryonic day 14.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS22: forebrain Present Regionally restricted 5P , 5O Expression in corticofugal axons with abnormal trajectories, displaced laterally in thick bundles, that do not cross pallial/subpallial boundary.

Specimen E18.5 wild-type not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus callosum Present Expression primarily in cells of cortical plate and marginal zone in hippocampus and corpus callosum.
TS26: cortical plate Present Expression primarily in cells of cortical plate and marginal zone in hippocampus and corpus callosum.
TS26: hippocampus marginal layer Present Expression primarily in cells of cortical plate and marginal zone in hippocampus and corpus callosum.

Specimen E18.5 Pax6-/- not shown: embryonic day 18.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS26: cortical plate Weak Reduced expression in cortical plate and marginal zone.
TS26: hippocampus marginal layer Weak Reduced expression in cortical plate and marginal zone.
TS26: pallium Present Regionally restricted Expression preserved mostly within medial pallium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory