Gene Expression Data
Assay Details
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Assay
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Reference:
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J:89119
Jones L, et al., Pax6 is required for the normal development of the forebrain axonal connections. Development. 2002 Nov;129(21):5041-52
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7736627
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Gene symbol:
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Pax6
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Gene name:
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paired box 6
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1B:
embryonic day 12.5; Pax6tm1Pgr/Pax6 +
(more  )
Specimen
1B:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: central nervous system |
Present |
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1B
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Distribution of expression very similar to expression of endogenous RNA.
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| TS20: eye |
Present |
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1B
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Distribution of expression very similar to expression of endogenous RNA.
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| TS20: pallium |
Present |
Regionally restricted |
1B
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Wider expression pattern in pallium,
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| TS20: cortical plate |
Present |
Regionally restricted |
1B
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Expression in postmitotic progenitors.
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Specimen
3C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: telencephalon |
Present |
Regionally restricted |
3C
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Authors report altered expression in ventral and lateral telencephalic areas
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Specimen
3D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: telencephalon |
Present |
Regionally restricted |
3D
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Authors report altered expression in ventral and lateral telencephalic areas
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Specimen
3K:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: subpallium |
Present |
Regionally restricted |
3K
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Expression in thalamocortical axons reaching ventral telencephalon.
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Specimen
4E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Regionally restricted |
4E
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Expression in narrow stripe linking cells of amygdala to cortex.
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Specimen
4G:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Regionally restricted |
4G
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Expression in dorsal cortex continued to ventral pallium at leteral surface. No expression in thickened pallial germinal neuroepithelium.
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Analysis Tools
