About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:162756 Bergwerff M, et al., Unique vascular morphology of the fourth aortic arches: possible implications for pathogenesis of type-B aortic arch interruption and anomalous right subclavian artery. Cardiovasc Res. 1999 Oct;44(1):185-96
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736357
Gene symbol: Vcl
Gene name: vinculin
Antibody: anti-vinculin (V4505), clone VIN-11-5
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3h: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: arch of aorta Present Widespread 3h Expression appeared more homogeneous throughout the aortic wall and does not clearly delineate an aberrant segment, but at decreased levels in the ring areas.
Specimen 4h: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: arch of aorta Present 4h Expression appeared more homogeneous throughout the aortic wall, apparently as much expressed in the aberrant vascular ring as it was in the rest of the aortic media, but was more prominent in the latter.
Specimen 5b/d: postnatal adult (more )
Structure Level Pattern Image Note
TS28: arch of aorta Present Regionally restricted 5d , 5b The aortic B-segment between the dotted lines was clearly aberrant in showing optically lower staining levels caused by reduced cellular volume of smooth muscle cells and increased elastic matrix.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory