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Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: RNA in situ
MGI Accession ID: MGI:7736306
Gene symbol: Reln
Gene name: reelin
Probe: Reln cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3E: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex marginal layer Cajal-Retzius cell Present Regionally restricted 3E Cajal-Retzius cells were marked by Reln.

Specimen 3F: embryonic day 12.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex marginal layer Cajal-Retzius cell Weak Regionally restricted 3F Expression was greatly reduced in the marginal zone of the double mutant.

Specimen S4A miR-9-2 +/+; miR9-3 +/+: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: pallium Cajal-Retzius cell Present S4A E14.5 top

Specimen S4A miR-9-2 -/-; miR9-3 -/-: embryonic day 14.5; Mir9-2tm1Sia/Mir9-2tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS22: pallium Cajal-Retzius cell Present S4A E14.5 bottom Single homozygous mutants didn't exhibit any apparent defects in neurogenesis.

Specimen S4B miR-9-2 +/+; miR9-3 +/+: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted S4B reelin top Expression was detected in layer I.

Specimen S4B miR-9-2 -/-; miR9-3 +/+: embryonic day 16.5; Mir9-2tm1Sia/Mir9-2tm1Sia (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present S4B reelin bottom Single homozygous mutants didn't exhibit any apparent defects in neurogenesis.

Specimen S5A miR-9-2 +/+; miR9-3 +/+: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: telencephalon Cajal-Retzius cell Present Regionally restricted S5A reelin top Expression was detected in Cajal-Retzius cells originated from rostral telencephalon. Septum derived Cajal-Retzius cells were indicated.

Specimen S5A miR-9-2 -/-; miR9-3 -/-: embryonic day 12.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS20: telencephalon Cajal-Retzius cell Present Regionally restricted S5A reelin bottom Septum-derived Cajal-Retzius cells appeared reduced in miR-9-2/3 double mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory