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Gene Expression Data
Assay Details
Assay
Reference: J:354175 Ueda Y, et al., Possible testosterone redundancy for 5alpha-dihydrotestosterone in the masculinization of mouse external genitalia. Exp Anim. 2022 Nov 10;71(4):451-459
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736228
Gene symbol: Srd5a2
Gene name: steroid 5 alpha-reductase 2
Antibody: anti-SRD5A2 (ab101896)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: male external genitalia Present Regionally restricted 5A Expression in entire corpus cavernosum.
Specimen 5B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus cavernosum of glans penis Present 5B Expression in entire corpus cavernosum.
Specimen 5C: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: corpus cavernosum of glans penis Present Regionally restricted 5C Expression gradually more prominent in peripheral region.
Specimen 5D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: corpus cavernosum of glans penis Present Regionally restricted 5D Expression gradually more prominent in peripheral region.
Specimen 5E: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: corpus cavernosum of glans penis Present Regionally restricted 5E Expression in surrounding sinusoidal spaces.
Specimen 6A/B/C: postnatal day 21 (more )
Note: Double labeled: green - Srd5a2; red - Acta2 (assay MGI:7736229).
Structure Cell Type Level Pattern Image Note
TS28: corpus cavernosum of glans penis blood vessel smooth muscle cell Present Regionally restricted 6B , 6A , 6C Expression co-localized with Acta2 in vascular smooth muscle cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory