About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:69569 DiPersio CM, et al., alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. J Cell Biol. 1997 May 5;137(3):729-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736213
Gene symbol: Col7a1
Gene name: collagen, type VII, alpha 1
Antibody: anti-type VII collagen
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Results
Specimen 4C: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: basement membrane Present 4C Expression is in the epidermal basement membrane.
TS27: epidermis Present 4C Expression is in the epidermal basement membrane.

Specimen 4G: postnatal newborn; Itga3tm1Jak/Itga3tm1Jak (more )
Structure Level Pattern Image Note
TS27: basement membrane Present 4G In this mutant staining is disorganized compared to wild-type.

Specimen 4K: postnatal newborn; Itga3tm1Jak/Itga3tm1Jak (more )
Structure Level Pattern Image Note
TS27: limb skin Present Regionally restricted 4K Expression is at the dermal and epidermal sides of the blister.

Specimen 6B: embryonic day 11.5; Itga3tm1Jak/Itga3tm1Jak (more )
Structure Level Pattern Image Note
TS19: integumental system Present 6B Expression in this mutant is the same as in wild-type.

Specimen 6D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: basement membrane Present 6D
TS23: dermis Present 6D

Specimen 6F: embryonic day 17.5; Itga3tm1Jak/Itga3+ (more )
Structure Level Pattern Image Note
TS25: basement membrane Present 6F
TS25: dermis Present 6F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory