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Gene Expression Data
Assay Details
Assay
Reference: J:332639 Rinta-Jaskari MM, et al., Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6;
Assay type: RNA in situ
MGI Accession ID: MGI:7735107
Gene symbol: Col18a1
Gene name: collagen, type XVIII, alpha 1
Probe: SXT-5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S1a WT: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Present S1a WT Expression in epithelium of ureter extending through kidney.
Specimen S1a -/-: embryonic day 12.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS20: metanephros Absent S1a Col18a1-/- No specific expression detected.
Specimen S1a P1/P1: embryonic day 12.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS20: ureteric trunk Present S1a Col18a1 P1/P1 Expression confined to ureteric stalk.
TS20: ureteric tip Absent S1a Col18a1 P1/P1
Specimen S1a P2/P2: embryonic day 12.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Present S1a Col18a1 P2/P2 Expression in epithelium of ureter extending through kidney.
Specimen S1b WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: metanephros Strong S1b WT
Specimen S1b -/-: embryonic day 13.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS21: metanephros Absent S1b Col18a1-/- No specific expression detected.
Specimen S1b P1/P1: embryonic day 13.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS21: metanephros Weak Regionally restricted S1b Col18a1 P1/P1 Significantly less expression at surface compared to wild type and P2/P2 mutant.
Specimen S1b P2/P2: embryonic day 13.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS21: metanephros Present S1b Col18a1 P2/P2
Specimen S1c WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metanephros Present S1c WT
Specimen S1c -/-: embryonic day 14.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS22: metanephros Absent S1c Col18a1-/- No specific expression detected.
Specimen S1c P1/P1: embryonic day 14.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS22: metanephros Weak Regionally restricted S1c Col18a1 P1/P1 Significantly less expression at surface compared to wild type and P2/P2 mutant.
Specimen S1c P2/P2: embryonic day 14.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS22: metanephros Present S1c Col18a1 P2/P2
Specimen S1d WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: ureteric tip Strong S1d WT
Specimen E16.5 -/- not shown: embryonic day 16.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS24: metanephros Absent
Specimen S1d P1/P1: embryonic day 16.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS24: metanephros Absent S1d Col18a1 P1/P1 No expression at surface of kidney, simlar to that of Col18a1-/- mutant (not shown).
Specimen S1d P2/P2: embryonic day 16.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS24: ureteric tip Strong S1d Col18a1 P2/P2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory